In vivo evaluation of [11C]preladenant for imaging of adenosine A2A receptors in the conscious monkey (#489) Xiaoyun Zhou 1, Erik de Vries 1, Kiichi Ishiwata 2,3,4, Muneyuki Sakata 2, Johan de Jong 1, Rudi Dierckx 1, Shingo Nishiyama 5, Hiroyuki Ohba 5, Hideo Tsukada 5, Philip Elsinga 1 1University Medical Center Groningen Nuclear Medicine & Molecular Imaging, Hanzeplein 1, 9713 GZ Groningen, Netherlands 2Tokyo Metropolitan Institute of Gerontology Research Team for Neuroimaging, 35-2, Sakae-cho, Tokyo, Tokyo 173-0015, Japan 3Southern TOHOKU Research Institute for Neuroscience Institute of Cyclotron and Drug Discovery Research, 7-115 Yatsuyamada, Koriyama 963-8052, Japan 4Fukushima Medical University Department of Biofunctional Imaging, 1 Hikarigaoka, Fukushima 960-1295, Japan 5Hamamatsu Photonics K.K. Central Research Laboratory, 5000 Hirakuchi, Hamamatsu 434-8601, Japan
14:00
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Bench to bedside: the GRPr antagonist Sarabesin 3 for prostate cancer imaging (#570) Ingrid L. Bakker 1, Alida C. Fröberg 1, Martijn B. Busstra 2, Theodosia Maina 3, Wytske van Weerden 2, Berthold A. Nock 3, Marion de Jong 1 1Erasmus MC Radiology & Nuclear Medicine, Postbus 2040, 3000 CA Rotterdam, Netherlands 2Erasmus MC Urology, Rotterdam, Netherlands 3NCSR Demokritos Molelular Radiopharmacy, Athens, Greece
14:30
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Feasibility of Affibody molecule-based PNA-mediated radionuclide pretargeting of malignant tumors (#488) Hadis Honarvar 1, Kristina Westerlund 2, Mohamed Altai 3, Mattias Sandström 4, Anna Orlova 5, Vladimir Tolmachev 6, Amelie Eriksson Karlström 7 1Uppsala University Department of Immunology, Genetics and Pathology, Rudbeck Laboratoriet, Uppsala, Sweden 2School of Biotechnology Division of Protein Technology, KTH Royal Institute of Technology, Stockholm, Sweden 3Uppsala University Department of Immunology, Genetics and Pathology, Rudbeck Laboratoriet, 75185 Uppsala, Sweden 4Section of Nuclear Medicine and PET Department of Surgical Sciences, Uppsala, Sweden 5Preclinical PET Platform Department of Medicinal Chemistry, Uppsala, Sweden 6Uppsala University Department of Immunology, Genetics and Pathology, Uppsala, Sweden 7School of Biotechnology Division of Protein Technology, Stockholm, Sweden